Group Isolation and Atherosclerosis in Cholesterol-fed Cockerels.
نویسندگان
چکیده
• It has been suggested that emotional stresses may be involved in the rate of development of atherosclerosis, may act to precipitate an acute arterial occlusion in the presence of atherosclerotic vascular disease, or, in the case of muscular organs like the heart, may serve to enhance the rate of activity of the organ beyond the capacity of the vasculature to prevent acute ischemia, thereby triggering an ischemia episode. Clinical studies on the role of psychological stresses in atherosclerosis are very difficult to carry out. The main reasons for these difficulties lie in the lack of a precise measure by which to characterize psychological stresses, and to adapt such stress evaluation to the reaction of a given individual." Studies on animals from the Philadelphia Zoological Garden indicate that over the past 50 years there was an increase in the occurrence of spontaneous arteriosclerosis in mammals and birds. The first increase was noted to occur following 1936 after drastic dietary changes. Since then, diet has been kept constant. Nevertheless, a second increase occurred with a change in distribution of the lesions. This second increase was attributed to changes in the environment of the animals, namely an increase in cage population, noise, and frequency of contact with man." Experimental results from the animal lab-
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ورودعنوان ژورنال:
- Circulation research
دوره 13 شماره
صفحات -
تاریخ انتشار 1963